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NF764

CAT: 0804-HY-161719-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-161719-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NF764 is a potent β-catenin (CTNNB1) degrader. NF764 reduces CTNNB1 protein levels in a proteasome-dependent manner. NF764 can be used in the study of cancer[1].
UNSPSC
12352005
Target
β-catenin
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nf764.html
Purity
99.28
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC(F)(F)C1=C(C2N(C(/C=C/C(C3=CC=CC=C3)=O)=O)CCC2)C=C(OC)C=C1
Molecular Formula
C22H20F3NO3
Molecular Weight
403.39
References & Citations
[1]Gowans FA, et al. Covalent Degrader of the Oncogenic Transcription Factor β-Catenin. bioRxiv [Preprint]. 2023 Nov 2:2023.10.31.565018.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T210201-01NF764

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