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Caulophyllogenin

CAT: 0804-HY-N7687-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N7687-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Caulophyllogenin is a triterpene saponin extracted from M. polimorpha. Caulophyllogenin is a partial PPARγ agonist, with an EC50 of 12.6 μM. Caulophyllogenin can be used for the research of type-2 diabetes, obesity, metabolic syndrome and inflammation[1][2].
CAS Number
52936-64-8
UNSPSC
12352211
Target
PPAR
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/caulophyllogenin.html
Solubility
10 mM in DMSO
Smiles
C[C@@]1(CO)[C@@H](O)CC[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])CC(C)(C)CC[C@@](C(O)=O)5[C@H](O)C[C@](C)4[C@@](C)3CC[C@@]12[H]
Molecular Formula
C30H48O5
Molecular Weight
488.70
References & Citations
[1]Montanari R, et, al. Screening of saponins and sapogenins from Medicago species as potential PPARγ agonists and X-ray structure of the complex PPARγ/caulophyllogenin. Sci Rep. 2016 Jun 10; 6:27658.|[2]Zhang Y, et, al. Studies on cytotoxic triterpene saponins from the leaves of Aralia elata. Food Chem. 2013 May 1;138 (1) :208-13.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
PPARγ

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