Ebiratide

CAT: 0804-HY-19648Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-19648Size:1 Each

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Description

Ebiratide (HOE-427 free base) is an ACTH 4-9 derivative, which acts directly on the central nervous system and exhibits memory-enhancing efficacy. Ebiratide enhances acetycholine (ACh) metabolism in rat brain[1][2].

CAS Number

105611-68-5

Product Name Alternative

HOE-427 (free base)

UNSPSC

12352209

Target

Melanocortin Receptor; nAChR

Type

Peptides

Related Pathways

GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ebiratide.html

Solubility

10 mM in DMSO

Smiles

NCCCCCCCCNC([C@H](CC1=CC=CC=C1)NC([C@@H](CCCCN)NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@@H](N)CCS(C)(=O)=O)=O)=O)CC3=CN=CN3)=O)=O)=O)=O

Molecular Formula

C48H73N11O10S

Molecular Weight

996.23

References & Citations

[1]Hock FJ, et al., Learning and memory processes of an ACTH4-9 analog (ebiratide; Hoe 427) in mice and rats. Peptides. 1988 May-Jun;9 (3) :575-81. |[2]G Wiemer, et al. Neurochemical effects of the synthetic ACTH4-9-analog Hoe 427 (Ebiratide) in rat brain. Peptides. 1988 Sep-Oct;9 (5) :1081-7.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

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