Lyso-PAF C-18

Lyso-PAF C-18

• CAS Number: 74430-89-0
• UNSPSC Description: Lyso-PAF C-18 is an intermediate for the synthesis of C18-PAF (HY-130345). It has an easily substituted "Lyso-PAF" structure and is easy to purify and has high yield. C18-PAF is a ligand for platelet-activating factor and PAF G protein-coupled receptor (PAFR) and has renovasodilator properties and antihypertensive lipid properties[1][2].
• Target Antigen: Endogenous Metabolite; Platelet-activating Factor Receptor (PAFR)
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Metabolic Enzyme/Protease
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/lyso-paf-c-18.html
• Solubility: 10 mM in DMSO
• Smiles: CCCCCCCCCCCCCCCCCCOC[C@@H](O)COP(OCC[N+](C)(C)C)([O-])=O
• Molecular Weight: 509.70
• References & Citations: [1]Heymans F, et al. New total synthesis and high resolution 1H NMR spectrum of platelet-activating factor, its enantiomer and racemic mixtures[J]. Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism, 1981, 666(2): 230-237.|[2]Vargaftig BB, et al. Background and present status of research on platelet-activating factor (PAF-acether). Ann N Y Acad Sci. 1981;370:119-37.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported