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Rabeximod

CAT: 0804-HY-14750-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14750-01Size:1 mg
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Description
Rabeximod (ROB-803), an anti-rheumatic compound, impairs the differentiation and function of human pro-inflammatory dendritic cells and macrophages via downregulating TLR2 and TLR4 stimulation. Rabeximod (ROB-803) is used for rheumatoid arthritis (RA) research[1].
CAS Number
872178-65-9
Product Name Alternative
ROB-803
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rabeximod.html
Solubility
10 mM in DMSO
Smiles
O=C(CN1C2=NC3=C(N=C2C4=C1C=CC(Cl)=C4)C=C(C)C(C)=C3)NCCN(C)C
Molecular Formula
C22H24ClN5O
Molecular Weight
409.91
References & Citations
[1]Pablo Giusti, et al. The novel anti-rheumatic compound Rabeximod impairs differentiation and function of human pro-inflammatory dendritic cells and macrophages. Immunobiology. 2011 Jan-Feb;216 (1-2) :243-50.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
TLR2; TLR4

Alternative Products

CatalogName
M34686-01Rabeximod

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