Emlenoflast

• UNSPSC Description:

  Emlenoflast (MCC7840), a sulfonylurea, is a potent and selective inhibitor of NLRP3 inflammasome, with an IC50 of [1][2].

• Target Antigen:

  NOD-like Receptor (NLR)

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/mcc7840.html

• Smiles:

  O=S(C1=NN(C(C)C)C=C1)(NC(NC2=C3CCCC3=CC4=C2CCC4)=O)=O

• Molecular Weight:

  388.48

• References & Citations:

  [1]El-Sharkawy LY, et, al. Inhibiting the NLRP3 Inflammasome. Molecules. 2020 Nov 25;25(23):5533.|[2]O'neill L, et, al. Sulfonylureas and related compounds and use of same. WO2016131098A1.

• Shipping Conditions:

  Room Temperature

• CAS Number:

  1995067-59-8