Dovitinib-RIBOTAC

Dovitinib-RIBOTAC

• CAS Number: 2759351-68-1
• UNSPSC Description: Dovitinib RIBOTAC is a targeted RNA degrader that cleaves pre-miR-21 with enhanced potency and selectivity.
• Target Antigen: PROTACs
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/dovitinib-ribotac.html
• Solubility: DMSO : 130 mg/mL (ultrasonic)
• Smiles: O=C1C(C2=NC3=CC(N4CCN(CCNC(NCCOCCOCCOCCOC5=C(O)C=C(/C=C6C(C(C(OCC)=O)=C(NC7=CC=CC=C7)S/6)=O)C=C5)=O)CC4)=CC=C3N2)=C(N)C8=C(C=CC=C8F)N1
• Molecular Weight: 1006.11
• References & Citations: [1]Zhang P, et al. Reprogramming of Protein-Targeted Small-Molecule Medicines to RNA by Ribonuclease Recruitment. J Am Chem Soc. 2021 Aug 25;143(33):13044-13055.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported