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Synaptamide

CAT: 0804-HY-100197-01Size: 5 mg (67 mM x 200 μL in Ethanol)Dry Ice: NoHazardous: No
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CAT#:0804-HY-100197-01Size:5 mg (67 mM x 200 μL in Ethanol)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Synaptamide (Dehydroepiandrosteron; DHEA) is an endogenous metabolite and structural analogue of Anandamide. Synaptamide binds to both the cannabinoid-1 and 2 (CB1 and CB2) cannabinoid receptors and has anti-inflammatory properties. Synaptamide is the first small-molecule endogenous ligand of an adhesion G protein-coupled receptor (aGPCR) [1] [2][3].
CAS Number
162758-94-3
Product Name Alternative
N-Docosahexaenoyl ethanolamine (DHEA) ; Docosahexaenoyl ethanolamide
UNSPSC
12352211
Hazard Statement
H225, H319
Target
Cannabinoid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Synaptamide.html
Concentration
67 mM * 400 μL in Ethanol
Purity
99.30
Solubility
Ethanol : 25 mg/mL (ultrasonic)
Smiles
CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(NCCO)=O
Molecular Formula
C24H37NO2
Molecular Weight
371.56
Precautions
H225, H319
References & Citations
[1]Kim HY, et al. Synaptamide, endocannabinoid-like derivative of docosahexaenoic acid with cannabinoid-independent function. Prostaglandins Leukot Essent Fatty Acids. 2013 Jan;88 (1) :121-5.|[2]Rashid MA, et al. N-Docosahexaenoylethanolamine is a potent neurogenic factor for neural stem cell differentiation. J Neurochem. 2013 Jun;125 (6) :869-84.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CB1; CB2

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