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APP Antibody

CAT: 0013-GTR17946220-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR17946220-02Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This APP Recombinant monoclonal Antibody is an unconjugated monoclonal product. It tagets APP using a a synthesized peptide derived from human Amyloid beta A4 as the immunogen. This antibody is suitable for ELISA, IF, WB. Purification: Affinity-chromatography.
Product Name Alternative
Amyloid-beta A4 protein (ABPP) (APPI) (APP) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta precursor protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP, Soluble APP-alpha (S-APP-alpha), Soluble APP-beta (S-APP-beta), C99 (Beta-secretase C-terminal fragment) (Beta-CTF), Amyloid-beta protein 42 (Abeta42) (Beta-APP42), Amyloid-beta protein 40 (Abeta40) (Beta-APP40), C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF), P3 (42), P3 (40), C80, Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID (59) ) (Gamma-CTF (59) ), Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID (57) ) (Gamma-CTF (57) ), Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID (50) ) (Gamma-CTF (50) ), C31], APP, A4 AD1
UniProt
P05067
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Amyloid beta A4
Target
APP
Clonality
Monoclonal
Clone
B8H32
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Affinity-chromatography
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ELISA, IF, WB
Host or Source
Rabbit
Preservative
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Isotype
Rabbit IgG

UniProtKB · P05067

Amyloid-beta precursor protein

A4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P05067
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
APP
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
APP
EC number
—
Processing
Precursor
Secondary accessions
B2R5V1, B4DII8, D3DSD1, D3DSD2, D3DSD3, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q6GSC0, Q8WZ99, Q9BT38, Q9UC33, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Alzheimer diseaseAmyloidosisDisease variantNeurodegeneration

Cellular component

AmyloidCell membraneCell projectionCoated pitCytoplasmCytoplasmic vesicleEndoplasmic reticulumEndosomeGolgi apparatusMembraneNucleusSecreted

Biological process

ApoptosisCell adhesionEndocytosisNotch signaling pathway

Ligand

CopperIronMetal-bindingZinc

PTM

Disulfide bondGlycoproteinIsopeptide bondOxidationPhosphoproteinProteoglycanSulfationUbl conjugation

Molecular function

Heparin-bindingProtease inhibitorSerine protease inhibitor

Domain

SignalTransmembraneTransmembrane helix

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