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Elimusertib-d3

CAT: 0804-HY-101566S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101566S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Elimusertib-d3 (BAY 1895344-d3) is the deuterium labeled Elimusertib (BAY 1895344) . Elimusertib is a potent, orally active and selective ATR inhibitor and has anti-tumor activity[1].
Product Name Alternative
BAY 1895344-d3
UNSPSC
12352005
Target
ATM/ATR
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
98.94
Solubility
DMSO : 5.4mg/mL (ultrasonic)
Smiles
C[C@H]1N(C2=CC(C3=CC=NN3C([2H])([2H])[2H])=C(C=CN=C4C5=CC=NN5)C4=N2)CCOC1
Molecular Formula
C20H18D3N7O
Molecular Weight
378.45
References & Citations
[1]Ulrich T. Luecking, et al. Abstract 983: Identification of potent, highly selective and orally available ATR inhibitor BAY 1895344 with favorable PK properties and promising efficacy in monotherapy and combination in preclinical tumor models. Cancer Research. July 2017 Volume 77, Issue 13 Supplement.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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