ANGPTL4 Polyclonal antibody

Angiopoietin-related protein 4 (ANGPTL4) is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity) . In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM) . The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.

Angptl4

Q9Z1P8

Human

Recombinant Mouse ANGPTL4 protein expressed by Mammalian

ARP; Secreted protein Bk; Angiopoietin-like protein; Angiopoietin-related protein; ANGPTL;425O18;425O18-1; Angiopoietin-like protein 4; Angiopoietin-related protein 4; ARP4; Fasting-induced adipose factor; Hepatic fibrinogen/angiopoietin-related protein; HFARP; NL2; PGAR; pp1158; Secreted protein Bk89; Farp; Fiaf; Ng27; Angptl4

Unconjugated

WB

Antigen Affinity Purification

1 mg/mL

WB 1:500-1:1000

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light.

45 kDa

50 kDa