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Biotin-PEG4-SS-azide

CAT: 0804-HY-139107-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-139107-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Biotin-PEG4-SS-azide is a cleavable, biotin-labeled, ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Biotin-PEG4-SS-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
UNSPSC
12352203
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/biotin-peg4-ss-azide.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCOCCOCCOCCOCCC(NCCSSCCC(NCCCN=[N+]=[N-])=O)=O)CCCC[C@H]1SC[C@@]([C@@]1([H])N2)([H])NC2=O
Molecular Formula
C29H52N8O8S3
Molecular Weight
736.97
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Disulfide Cleavable Linker

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