Products for Research Use Only
RegisterLogin

Amcasertib

CAT: 0804-HY-17602-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-17602-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Amcasertib (BBI503) is an orally activate cancer stemness kinase inhibitor that enhances apoptosis. Amcasertib inhibits the expression of NANOG and CD133 and cell viability in PC-9/GR cells.
CAS Number
1129403-56-0
Product Name Alternative
BBI503
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Amcasertib.html
Purity
98.03
Solubility
DMSO : ≥ 30 mg/mL
Smiles
O=C(C1=C(C)NC(/C=C2C(NC3=C/2C=C(C4=CSC(C5=CC=CC=C5)=N4)C=C3)=O)=C1C)NCCN(CC)CC
Molecular Formula
C31H33N5O2S
Molecular Weight
539.69
Precautions
H302, H315, H319, H335
References & Citations
[1]Jia Z, et al. 1,25-dihydroxyvitamin D3 signaling-induced decreases in IRX4 inhibits NANOG-mediated cancer stem-like properties and gefitinib resistance in NSCLC cells. Cell Death Dis. 2020;11 (8) :670
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
TRC-A634611-250MGAmcasertib
EVB40356-01Amcasertib (BBI503)
A16850-25Amcasertib (BBI503) 25mg
A16850-10Amcasertib (BBI503) 10mg
A16850-500Amcasertib (BBI503) 500mg
A16850-1Amcasertib (BBI503) 1mg
A16850-100Amcasertib (BBI503) 100mg
A16850-5Amcasertib (BBI503) 5mg
A16850-2Amcasertib (BBI503) 2mg
A16850-50Amcasertib (BBI503) 50mg

Popular Products