Furaltadone (hydrochloride)

Furaltadone (hydrochloride)

• CAS Number: 3759-92-0
• UNSPSC Description: Furaltadone hydrochloride is an orally active antibacterial agent that can be used for the study of intestinal Salmonella infections. Furaltadone has in vitro inhibitory effects on Staphylococcus. In addition, Furaltadone shows inhibitory effects on allergic reactions[1][2][3].
• Target Antigen: Bacterial
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/Furaltadone-hydrochloride.html
• Purity: 99.31
• Solubility: DMSO : 16.67 mg/mL (ultrasonic)|H2O : ≥ 25 mg/mL
• Smiles: O=C1OC(CN2CCOCC2)CN1/N=C/C3=CC=C([N+]([O-])=O)O3.[H]Cl
• Molecular Weight: 360.75
• References & Citations: [1]A.Rampling(Dr.), et al. The effect of furaltadone, a nitrofuran drug, on experimental infections of chickens with salmonella enteritidis phage Type 4. Pathology Volume 25, Supplement 1, 1993, Page 22.|[2]William R. McCabe, et al. Furaltadone — A Critical Evaluation of Clinical and Laboratory Studies. N Engl J Med 1960; 263:927-934.|[3]Nam ST, et al. Furaltadone suppresses IgE-mediated allergic response through the inhibition of Lyn/Syk pathway in mast cells. Eur J Pharmacol. 2018 Jun 5;828:119-125.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: Phase 2