Terbutaline

• Description :

  Terbutaline is an orally active β2-adrenergic receptor agonist and an active metabolite of bambuterol[1]. Terbutaline can be used in asthma symptom research[2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H312, H332

• Target :

  Adrenergic Receptor; Antibiotic; Drug Metabolite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/terbutaline.html

• Purity :

  99.77

• Solubility :

  DMSO : 233.33 mg/mL (ultrasonic)

• Smiles :

  OC1=CC(C(O)CNC(C)(C)C)=CC(O)=C1

• Molecular Formula :

  C12H19NO3

• Molecular Weight :

  225.29

• Precautions :

  H302, H312, H332

• References & Citations :

  [1]Mohamed Ismail NA, et al. Nifedipine versus terbutaline for tocolysis in external cephalic version. Int J Gynaecol Obstet. 2008 Sep;102 (3) :263-6.|[2]Joana A Loureiro, et al. The interaction of a β2 adrenoceptor agonist drug with biomimetic cell membrane models: The case of terbutaline sulphate. Life Sci. 2021 Nov 15;285:119992.|[3]Tiina Keränen, et al. Anti-Inflammatory Effects of β2-Receptor Agonists Salbutamol and Terbutaline Are Mediated by MKP-1. PLoS One. 2016 Feb 5;11 (2) :e0148144.|[4]Nada Choucair-Jaafar, et al. The antiallodynic action of nortriptyline and terbutaline is mediated by β (2) adrenoceptors and δ opioid receptors in the ob/ob model of diabetic polyneuropathy. Brain Res. 2014 Feb 10;1546:18-26.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• Isoform :

  β adrenergic receptor

• CAS Number :

  [23031-25-6]