Mal-PEG2-acid

• UNSPSC Description:

  Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule[1]. Mal-PEG2-acid is also a PROTAC linker that can be used in the synthesis of PROTACs.

• Target Antigen:

  ADC Linker; PROTAC Linkers

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related;PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mal-peg2-acid.html

• Purity:

  99.90

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)CCOCCOCCN1C(C=CC1=O)=O

• Molecular Weight:

  257.24

• References & Citations:

  [1]Zhao, Yongxin, et al. Cytotoxin molecule, conjugate and preparation method and application thereof. Faming Zhuanli Shenqing (2019), CN 109912683 A 20190621.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1374666-32-6