Mal-PEG2-acid

CAT: 0804-HY-130442-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-130442-01Size:100 mg
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Description
Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule[1]. Mal-PEG2-acid is also a PROTAC linker that can be used in the synthesis of PROTACs.
CAS Number
[1374666-32-6]
UNSPSC
12352203
Hazard Statement
H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-peg2-acid.html
Purity
99.90
Solubility
10 mM in DMSO
Smiles
O=C(O)CCOCCOCCN1C(C=CC1=O)=O
Molecular Formula
C11H15NO6
Molecular Weight
257.24
Precautions
H315, H319, H335
References & Citations
[1]Zhao, Yongxin, et al. Cytotoxin molecule, conjugate and preparation method and application thereof. Faming Zhuanli Shenqing (2019), CN 109912683 A 20190621.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker; PEG Linkers

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