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Ramentaceone

CAT: 0804-HY-121684Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-121684Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ramentaceone (7-Methyljuglon), a naphthoquinone that can be isolated from Drosera sp., inhibits PI3K activity. Ramentaceone (7-Methyljuglon) reduces the expression of the PI3K protein and inhibits the phosphorylation of the Akt protein in breast cancer cells. Ramentaceone (7-Methyljuglon) induces apoptosis[1].
CAS Number
14787-38-3
Product Name Alternative
7-Methyljuglon
UNSPSC
12352005
Hazard Statement
H301-H315-H319
Target
Apoptosis; PI3K
Type
Natural Products
Related Pathways
Apoptosis; PI3K/Akt/mTOR
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ramentaceone.html
Solubility
10 mM in DMSO
Smiles
O=C1C=CC(C2=C1C=C(C)C=C2O)=O
Molecular Formula
C11H8O3
Molecular Weight
188.18
Precautions
P264-P270-P280-P302+P352-P330-P362+P364-P405-P501
References & Citations
[1]Anna Kawiak, et al. Ramentaceone, a Naphthoquinone Derived from Drosera sp., Induces Apoptosis by Suppressing PI3K/Akt Signaling in Breast Cancer Cells. PLoS One. 2016 Feb 3;11 (2) :e0147718.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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MBS5774450Ramentaceone

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