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Cajanin

CAT: 0804-HY-N2983Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N2983Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cajanin is a potent and orally active anti-melanogenic agent. Cajanin shows antiproliferative activity in MNT1 Cells. Cajanin efficiently decreases the melanin content. Cajanin down-regulates the mRNA and protein expression levels of MITF, tyrosinase, TRP-1 and Dct (TRP-2) . Cajanin induces cell cycle arrest at G2/M and S phase. Cajanin stimulates osteoblast proliferation. Cajanin has the potential for the research of human hyperpigmented disorders and menopausal osteoporosis[1][2].
CAS Number
32884-36-9
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Tyrosinase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cajanin.html
Purity
99.96
Smiles
O=C1C2=C(O)C=C(OC)C=C2OC=C1C3=C(C=C(O)C=C3)O
Molecular Formula
C16H12O6
Molecular Weight
300.26
Precautions
H315, H319
References & Citations
[1]Netcharoensirisuk P, et al. Cajanin Suppresses Melanin Synthesis through Modulating MITF in Human Melanin-Producing Cells. Molecules. 2021 Oct 5;26 (19) :6040.|[2]Bhargavan B, et al. Methoxylated isoflavones, cajanin and isoformononetin, have non-estrogenic bone forming effect via differential mitogen activated protein kinase (MAPK) signaling. J Cell Biochem. 2009 Oct 1;108 (2) :388-99.|[3]Wensaas AJ, et al. Fatty acid incubation of myotubes from humans with type 2 diabetes leads to enhanced release of beta-oxidation products because of impaired fatty acid oxidation: effects of tetradecylthioacetic acid and eicosapentaenoic acid. Diabetes. 2009 Mar;58 (3) :527-35.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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