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Etoricoxib (Standard)

CAT: 0804-HY-15321R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15321R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Etoricoxib (Standard) is the analytical standard of Etoricoxib. This product is intended for research and analytical applications. Etoricoxib (MK-0663) is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood.
CAS Number
202409-33-4
Product Name Alternative
MK-0663 (Standard) ; L-791456 (Standard)
UNSPSC
12352005
Hazard Statement
H302, H310
Target
COX; Reference Standards
Type
Reference Standards
Related Pathways
Immunology/Inflammation; Others
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/etoricoxib-standard.html
Purity
99.92
Smiles
O=S(C1=CC=C(C2=CC(Cl)=CN=C2C3=CC=C(C)N=C3)C=C1)(C)=O
Molecular Formula
C18H15ClN2O2S
Molecular Weight
358.84
Precautions
H302, H310
References & Citations
[1]Riendeau D, et al.Etoricoxib (MK-0663) : preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2. J Pharmacol Exp Ther. 2001 Feb;296 (2) :558-66.|[2]Kunak CS, et al. The Effect of Etoricoxib on Hepatic Ischemia-Reperfusion Injury in Rats. Oxid Med Cell Longev. 2015;2015:598162.|[3]Tanwar L, et al. Anti-proliferative and apoptotic effects of etoricoxib, a selective COX-2 inhibitor, on 1,2-dimethylhydrazine dihydrochloride-induced colon carcinogenesis. Asian Pac J Cancer Prev. 2010;11 (5) :1329-33.
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
Launched

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HY-Z4710-01Etoricoxib impurity 17
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HY-Z4705-01Etoricoxib impurity 7
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CatalogName
A3405-5.1Etoricoxib

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