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Oosporein

CAT: 0804-HY-N7719-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N7719-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oosporein is a microbial metabolite and a red crystalline toxin produced by various fungi. Oosporein can promote the reproduction of fungi in host bodies by inhibiting insect immunity, and possesses multiple activities such as antibacterial, antiviral (HSV), and insecticidal effects. Oosporein can inhibit plant growth. In addition, Oosporein can also induce apoptosis, cell membrane damage, oxidative stress, and mitochondrial damage. Oosporein has certain antitumor activity[1][2][3][4][5].
CAS Number
475-54-7
UNSPSC
12352211
Target
Apoptosis; Bacterial; Caspase; Endogenous Metabolite; Fungal; HSV; Parasite; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/oosporein.html
Purity
99.16
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C(C(C)=C1O)C(O)=C(C2=C(O)C(C(C)=C(O)C2=O)=O)C1=O
Molecular Formula
C14H10O8
Molecular Weight
306.22
References & Citations
[1]Cole RJ, et al. Toxic effects of oosporein from Chaetomium trilaterale. J Agric Food Chem. 1974;22 (3) :517-520.|[2]Taniguchi M, et al. Antimicrobial and Respirationinhibitory Activities of Oosporein. Agricultural and biological chemistry, 1984, 48 (4) : 1065-1067.|[3]Feng P, et al. C. Fungal biosynthesis of the bibenzoquinone oosporein to evade insect immunity. Proc Natl Acad Sci U S A. 2015 Sep 8;112 (36) :11365-70.|[4]Mao B Z, et al. Separation and determination of the bioactivity of oosporein from Chaetomium cupreum. African Journal of Biotechnology, 2010, 9 (36) .|[5]Ramesha A, et al. Cytotoxic effects of oosporein isolated from endophytic fungus Cochliobolus kusanoi. Front Microbiol. 2015 Sep 1;6:870.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Caspase 3; Caspase 6; Caspase 9; Microbial Metabolite

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CatalogName
BA7630-1Oosporein

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