Products for Research Use Only
RegisterLogin

Quassin

CAT: 0804-HY-N1581-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N1581-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Quassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits P. falciparum with an IC50 of 0.15 μM. Quassin possesses reversible antifertility, anti-estrogenic and anti-plasmodial activity[1][2].
CAS Number
76-78-8
Product Name Alternative
Nigakilactone D
UNSPSC
12352005
Hazard Statement
H302
Target
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Infection; Endocrinology
Assay Protocol
https://www.medchemexpress.com/quassin.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C[C@@H]([C@@]1(C[C@]2(OC(C[C@]([C@]2([C@]3([C@@]41C)[H])C)(C(C)=C(OC)C3=O)[H])=O)[H])[H])C=C(OC)C4=O
Molecular Formula
C22H28O6
Molecular Weight
388.45
Precautions
H302
References & Citations
[1]Raji Y, et al. Reproductive activities of female albino rats treated with quassin, a bioactive triterpenoid from stem bark extract of Quassia amara. Niger J Physiol Sci. 2010 Nov 24;25 (2) :95-102.|[2]Mishra K, et al. Plasmodium falciparum: in vitro interaction of quassin and neo-quassin with artesunate, a hemisuccinate derivative of artemisinin. Exp Parasitol. 2010 Apr;124 (4) :421-7.|[3]Njar VC, et al. Antifertility activity of Quassia amara: quassin inhibits the steroidogenesis in rat Leydig cells in vitro. Planta Med. 1995 Apr;61 (2) :180-2.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Plasmodium

Alternative Products

CatalogName
CS-T-61001Quassin
TRC-Q509403-5MGQuassin (~90%)
AR-Q03818-01Quassin-d6
TRC-Q509400-2.5MGQuassin (Mixture of Quassin, Isoquassin and Neoquassin)
XQ161591-01Quassin - 98%
TRC-Q509404-1MGQuassin (>95%)
Q00035Quassin (powdered extract of quassia chips) 53-57% total Quasisin + Neoquassin and 11-16% Quassin

Popular Products