Timonacic

• Description :

  Timonacic (1,3-Thiazolidine-4-carboxylic acid) is an orally active thiol antioxidant. Timonacic has anti-aging and anti-hepatotoxic effects. Timonacic has a LD50 of 400 mg/kg for mice. Timonacic can be used in the research of liver diseases, gastrointestinal diseases, and cancer[1][2].

• CAS Number :

  [444-27-9]

• Product Name Alternative :

  1,3-Thiazolidine-4-carboxylic acid

• UNSPSC :

  12352005

• Hazard Statement :

  H301, H312+H332, H315, H319, H335

• Target :

  Amino Acid Derivatives

• Type :

  Reference compound

• Related Pathways :

  Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer; Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/Timonacic.html

• Concentration :

  10mM

• Purity :

  98.0

• Solubility :

  DMSO : 6 mg/mL (ultrasonic) |H2O : 14.29 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=C(C1NCSC1)O

• Molecular Formula :

  C4H7NO2S

• Molecular Weight :

  133.17

• Precautions :

  H301, H312+H332, H315, H319, H335

• References & Citations :

  [1]Bakry RS, et al. Spectrophotometric investigation of the formed chelate between timonacic and palladium (II) and its analytical applications. J Pharm Biomed Anal. 1998 May;17 (1) :95-101.|[2]H U Weber, et al. Thiazolidine-4-carboxylic acid, a physiologic sulfhydryl antioxidant with potential value in geriatric medicine. Arch Gerontol Geriatr. 1982 Dec;1 (4) :299-310.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported