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NU2058

CAT: 0804-HY-19316-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-19316-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NU2058 (O6- (Cyclohexylmethyl) guanine) is a potent, competitive and guanine-based CDK inhibitor with IC50s of 17 μM and 26 μM for CDK2 and CDK1. NU2058 has anti-cancer activity.
CAS Number
161058-83-9
Product Name Alternative
O6- (Cyclohexylmethyl) guanine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/NU2058.html
Purity
99.66
Solubility
DMSO : ≥ 32 mg/mL
Smiles
NC1=NC(OCC2CCCCC2)=C3NC=NC3=N1
Molecular Formula
C12H17N5O
Molecular Weight
247.30
Precautions
H302, H315, H319, H335
References & Citations
[1]Rigas AC, et al. Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer. Oncogene. 2007 Dec 6;26 (55) :7611-7619.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK1; CDK2

Alternative Products

CatalogName
BUP13337-01NU2058
A15767-50NU2058 50mg
A15767-100NU2058 100mg
A15767-25NU2058 25mg
A15767-10NU2058 10mg
A15767-200NU2058 200mg
A15767-5NU2058 5mg
A15767-10mM-DNU2058 10mM * 1mL in DMSO

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