Sanguinarine

CAT: 0804-HY-N0052-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-N0052-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Sanguinarine (Sanguinarin), a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS) . Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.

CAS Number

2447-54-3

Product Name Alternative

Sanguinarin; Sanguinarium; Pseudochelerythrine

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Apoptosis; Autophagy

Type

Natural Products

Related Pathways

Apoptosis; Autophagy

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Sanguinarine.html

Solubility

10 mM in DMSO

Smiles

C[N+]1=CC2=C3C(OCO3)=CC=C2C(C=CC4=C5)=C1C4=CC6=C5OCO6

Molecular Formula

C20H14NO4

Molecular Weight

332.33

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Wang Y, Noninvasive bioluminescence imaging of the dynamics of sanguinarine induced apoptosis via activation of reactive oxygen species. Oncotarget. 2016 Apr 19;7 (16) :22355-67.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

Launched

Citation 01

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T2781-01	Sanguinarine
B5970-20	Sanguinarine chloride
MBS3610325-01	Dihydro Sanguinarine
GTR19228889-01	Sanguinarine nitrate
GTR19153851	Sanguinarine Sulfate

Sanguinarine

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