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Dibenzoylmethane

CAT: 0804-HY-W009731-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W009731-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dibenzoylmethane, a minor ingredient in licorice, activates Nrf2 and prevents various cancers and oxidative damage. Dibenzoylmethane, an analog of curcumin, results in dissociation from Keap1 and nuclear translocation of Nrf2[1].
CAS Number
120-46-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Keap1-Nrf2
Type
Natural Products
Related Pathways
NF-κB
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/dibenzoylmethane.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CC=C1)CC(C2=CC=CC=C2)=O
Molecular Formula
C15H12O2
Molecular Weight
224.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Mingnan Cao, et al. Dibenzoylmethane Protects Against CCl4-Induced Acute Liver Injury by Activating Nrf2 via JNK, AMPK, and Calcium Signaling. AAPS J. 2017 Nov;19 (6) :1703-1714.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
No Development Reported

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