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NLRP3 Antibody

CAT: 0864-A17642-50UGSize: 50 µgDry Ice: NoHazardous: No
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CAT#:0864-A17642-50UGSize:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Aliases
AGTAVPRL, AII/AVP, Angiotensin/vasopressin receptor AII/AVP like , Angiotensin/vasopressin receptor AII/AVP-like, C1orf7, Caterpiller protein 1.1, CIAS 1, CIAS1, CLR1.1, Cold autoinflammatory syndrome 1, Cold autoinflammatory syndrome 1 protein, Cryopyrin, Familial cold autoinflammatory syndrome, FCAS, FCU, LRR and PYD domains-containing protein 3, Muckle-Wells syndrome, MWS, NACHT, NACHT LRR and PYD containing protein 3, NALP 3, NALP3, NALP3_HUMAN, NLR family pyrin domain containing 3, NLRP3, PYPAF 1, PYPAF1, PYRIN containing APAF1 like protein 1, PYRIN-containing APAF1-like protein 1
UniProt
Q96P20
Host
Rabbit
Antigen Species
Human
Reactivity
Human
Target Antigen
Synthesized peptide derived from the Internal region of Human Cryopyrin.
Target
NLRP3
Clonality
Polyclonal
Conjugation
Non-conjugated
Applications
WB, ELISA, WB:1:500-1:2000, ELISA:1:20000
Field of Research
Immunology
Purification Method
Antigen affinity purified
Form
Liquid
Buffer
PBS, 50% glycerol, 0.5% BSA, 0.02% sodium azide, pH 7.4.
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Fragment
IgG

UniProtKB · Q96P20

NACHT, LRR and PYD domains-containing protein 3

NLRP3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96P20
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NLRP3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.6.4.-
Processing
—
Secondary accessions
A0A024R5Q0, B2RC97, B7ZKS9, B7ZKT2, B7ZKT3, O75434, Q17RS2, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorHydrolase

PTM

ADP-ribosylationDisulfide bondIsopeptide bondLipoproteinPalmitatePhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Disease

AmyloidosisDeafnessDisease variantNon-syndromic deafness

Ligand

ATP-bindingNucleotide-binding

Cellular component

CytoplasmCytoskeletonEndoplasmic reticulumGolgi apparatusInflammasomeMembraneMitochondrionNucleusSecreted

Biological process

ImmunityInflammatory responseInnate immunityTranscriptionTranscription regulation

Domain

Leucine-rich repeatRepeat

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