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Apararenone

CAT: 0804-HY-109002-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-109002-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Apararenone (MT-3995) is a novel non-steroidal mineralocorticoid receptor antagonists under development for the treatment of diabetic nephropathies and non-alcoholic steatohepatitis.
CAS Number
945966-46-1
Product Name Alternative
MT-3995
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Mineralocorticoid Receptor
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Apararenone.html
Purity
99.09
Solubility
DMSO : ≥ 125 mg/mL
Smiles
O=C1N(C2=CC=C(F)C=C2)C3=CC=C(NS(C)(=O)=O)C=C3OC1(C)C
Molecular Formula
C17H17FN2O4S
Molecular Weight
364.39
Precautions
H302, H315, H319, H335
References & Citations
[1]Kolkhof P, et al. 30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Mineralocorticoid receptor antagonists: 60 years of research and development. J Endocrinol. 2017 Jul;234 (1) :T125-T140.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
MBS3606773-01Apararenone
A19480-2Apararenone 2mg
A19480-50Apararenone 50mg
A19480-10Apararenone 10mg
A19480-100Apararenone 100mg
A19480-25Apararenone 25mg
A19480-5Apararenone 5mg
A19480-10mM-DApararenone 10mM * 1mL in DMSO

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