EthD-III

• UNSPSC Description:

  EthD-III is a nucleic acid probe. EthD-III is a red fluorescent stain that can be used to detect dead cells. EthD-III enters cells with damaged membranes and binds to nucleic acids, resulting in bright red fluorescence in dead cells (Ex/Em=530/645 nm)[1][2].

• Target Antigen:

  DNA Stain

• Type:

  Dye Reagents

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/ethd-iii.html

• Purity:

  95.0

• Solubility:

  10 mM in DMSO

• Smiles:

  C[NH+](CCC[NH2+]CCC[N+]1=C(C2=CC(N)=CC=C2C3=C1C=C(C=C3)N)C4=CC=CC=C4)CCC[NH2+]CCC[N+]5=C(C6=CC(N)=CC=C6C7=C5C=C(C=C7)N)C8=CC=CC=C8

• Molecular Weight:

  978.36

• References & Citations:

  [1]Anastassov I, et al. Cytoprotection by endogenous zinc in the vertebrate retina. J Neurochem. 2014 Apr;129(2):249-55. |[2]Horie T, et al. OmpA-Like Proteins of Porphyromonas gingivalis Mediate Resistance to the Antimicrobial Peptide LL-37. J Pathog. 2018 Dec 27;2018:2068435.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light, stored under nitrogen)

• Clinical Information:

  No Development Reported