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Cefmetazole

CAT: 0804-HY-B1595-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1595-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cefmetazole (CS 1170) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative and anaerobic bacteria. Cefmetazole binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections[1][2][3].
CAS Number
56796-20-4
Product Name Alternative
CS 1170
UNSPSC
12352005
Hazard Statement
H315, H317, H319, H334, H335
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/cefmetazole.html
Purity
99.84
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#CCSCC(N[C@]1([C@]2([H])N(C(C(O)=O)=C(CS2)CSC3=NN=NN3C)C1=O)OC)=O
Molecular Formula
C15H17N7O5S3
Molecular Weight
471.53
Precautions
H315, H317, H319, H334, H335
References & Citations
[1]Truesdell SE, et, al. Interaction of cephalosporins with penicillin-binding proteins of methicillin-resistant Staphylococcus aureus. J Antimicrob Chemother. 1989 Apr;23 Suppl D:13-9.|[2]Schentag JJ. Cefmetazole sodium: pharmacology, pharmacokinetics, and clinical trials. Pharmacotherapy. 1991;11 (1) :2-19.|[3]Yaguchi Y, et, al. Influences of long-term antibiotic administration on Peyer's patch lymphocytes and mucosal immunoglobulin A levels in a mouse model. JPEN J Parenter Enteral Nutr. 2006 Sep-Oct;30 (5) :395-8; discussion 399.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β-lactam

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