Nerisopam

• Description :

  Nerisopam is an orally active gamma-aminobutyric acid (GABA) receptor agonist. Nerisopam is an anxiolytic and antipsychotic homophthalazine. Nerisopam induces rapid, intense expression of Fos-like immunoreactivity in the rostral, dorsomedial and lateral parts of the striatum in the rat[1].

• Product Name Alternative :

  GYKI52322; EGIS-6775

• UNSPSC :

  12352005

• Target :

  GABA Receptor

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/nerisopam.html

• Solubility :

  10 mM in DMSO

• Smiles :

  NC1=CC=C(C=C1)C2=NN=C(CC3=CC(OC)=C(C=C32)OC)C

• Molecular Formula :

  C18H19N3O2

• Molecular Weight :

  309.36

• References & Citations :

  [1]Palkovits M, et al. Anxiolytic homophthalazines increase Fos-like immunoreactivity in selected brain areas of the rat. Eur J Pharmacol. 1997 Jul 16;331 (1) :53-63.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• CAS Number :

  [102771-12-0]