Ifosfamide

• UNSPSC Description:

  Ifosfamide is an alkylating chemotherapeutic agent with activity against a wide range of tumors.

• Target Antigen:

  DNA Alkylator/Crosslinker

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ifosfamide.html

• Solubility:

  DMSO : ≥ 50 mg/mL

• Smiles:

  ClCCN1P(OCCC1)(NCCCl)=O

• Molecular Weight:

  261.089

• References & Citations:

  [1]Helal M. Prenatal effects of transplacental exposure to ifosfamide in rats. Biotech Histochem. 2016 Jul;91(5):357-68.|[2]Karle P, et al. Necrotic, rather than apoptotic, cell death caused by cytochrome P450-activated ifosfamide. Cancer Gene Ther. 2001 Mar;8(3):220-30.|[3]Vredenburg G, et al. Activation of the anticancer drugs cyclophosphamide and ifosfamide by cytochrome P450 BM3 mutants. Toxicol Lett. 2015 Jan 5;232(1):182-92.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  Launched

• CAS Number:

  3778-73-2