β-Casomorphin, bovine (TFA)

• UNSPSC Description:

  β-Casomorphin, bovine TFA (β-Casomorphin-7 (bovine) TFA) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay[1].

• Target Antigen:

  Opioid Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/beta-casomorphin-bovine-tfa.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N(CCC1)[C@@H]1C(NCC(N(CCC2)[C@@H]2C(N[C@H](C(O)=O)[C@@H](C)CC)=O)=O)=O)[C@@H](NC([C@H](CCC3)N3C([C@@H](N)CC4=CC=C(O)C=C4)=O)=O)CC5=CC=CC=C5.OC(C(F)(F)F)=O

• Molecular Weight:

  903.94

• References & Citations:

  [1]Brantl V, et al. Opioid activities of beta-casomorphins. Life Sci. 1981 Apr 27;28(17):1903-9.|[2]Zoghbi S, et al. β-casomorphin-7-7 regulates the secretion and expression of gastrointestinal mucins through a μ-opioid pathway. Am J Physiol Gastrointest Liver Physiol. 2006 Jun;290(6):G1105-13.|[3]Zhang W, et al. The protective effects of beta-casomorphin-7 against glucose -induced renal oxidative stress in vivo and vitro. PLoS One. 2013 May 3;8(5):e63472.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported