RegisterLogin

Antcin A

CAT: 0804-HY-N9921-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N9921-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Antcin A is a potent NLRP3 inhibitor that inhibits the assembly and activation of the NLRP3 inflammasome. Antcin A can inhibit Kupffer cell pyroptosis and has liver protective activity. Antcin A can be used to study inflammation, such as non-alcoholic fatty liver disease[1].
CAS Number
[163597-24-8]
UNSPSC
12352211
Target
NOD-like Receptor (NLR) ; Pyroptosis
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/antcin-a.html
Purity
99.71
Solubility
10 mM in DMSO
Smiles
C[C@@]12C3=C(CC[C@@]1([H])[C@@H](C(CC2)=O)C)[C@@]4([H])[C@](CC3=O)([C@@](CC4)([H])[C@H](C)CCC(C(C)C(O)=O)=C)C
Molecular Formula
C29H42O4
Molecular Weight
454.64
References & Citations
[1]Ruan S, et al. Antcin A alleviates pyroptosis and inflammatory response in Kupffercells of non-alcoholic fatty liver disease by targeting NLRP3. Int Immunopharmacol. 2021 Nov;100:108126.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P4074Anti-BetaGamma
HY-P9920A-01Ramucirumab (anti-VEGFR)
HY-P9906A-01Bevacizumab (Anti-VEGFA)
HY-P9928A-01Alirocumab (anti-PCSK9)
HY-P990360-01Anti-CD9 Antibody
HY-P990467-01Anti-MICB Antibody
HY-P990338Anti-ASIC1 Antibody
HY-P990335-01Anti-ANGPTL4 Antibody
HY-P990352-01Anti-CD36 Antibody
HY-P990429Anti-Hepsin Antibody

Alternative Products

CatalogName
BUP01813-01Antcin A
TN10265-01Antcin B
T80010-01(25S) -Antcin B
MBS5821669(25S)-Antcin B
RM-Z240000-01S-Antcin K; Zhankuic acid K

Popular Products