Products for Research Use Only
RegisterLogin

BIBF0775

CAT: 0804-HY-13783-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-13783-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
BIBF0775 is a potent and selective transforming growth factor β (TGFβ) type I receptor (Alk5) inhibitor with an IC50 of 34 nM.
CAS Number
334951-90-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
TGF-β Receptor
Type
Reference compound
Related Pathways
TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/BIBF0775.html
Purity
99.42
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(NC/2=O)=C(C=C1)C2=C(C3=CC=CC=C3)\NC4=CC=C(CN5CCCCC5)C=C4)N(CC)C
Molecular Formula
C31H34N4O2
Molecular Weight
494.63
Precautions
H302, H315, H319, H335
References & Citations
[1]Roth GJ, et al. Design, synthesis, and evaluation of indolinones as inhibitors of the transforming growth factor β receptor I (TGFβRI) . J Med Chem. 2010 Oct 28;53 (20) :7287-95.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
BA9164-50BIBF0775
A17230-200BIBF0775 200mg
A17230-100BIBF0775 100mg
A17230-25BIBF0775 25mg
A17230-1BIBF0775 1mg
A17230-5BIBF0775 5mg
A17230-50BIBF0775 50mg
A17230-10BIBF0775 10mg
A17230-10mM-DBIBF0775 10mM * 1mL in DMSO

Popular Products