CXCL1 / GRO alpha Recombinant Rabbit Monoclonal Antibody [PSH07-53]

CXCL1 / GRO alpha Recombinant Rabbit Monoclonal Antibody [PSH07-53]

• Description: Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha (4-73), GRO-alpha (5-73) and GRO-alpha (6-73) show a 30-fold higher chemotactic activity. This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.
• Product Name Alternative: C-X-C motif chemokine 1 antibody Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) antibody chemokine (C-X-C motif) ligand 1 antibody CINC-1 antibody CXCL1 antibody Cytokine-induced neutrophil chemoattractant 1 antibody Fibroblast secretory protein antibody Fsp antibody Gro 1 antibody Gro A antibody Gro antibody GRO protein, alpha antibody GRO-alpha (1-73) antibody GRO-alpha (6-73) antibody Gro1 antibody GRO1 oncogene (melanoma growth stimulating activity, alpha) antibody GRO1 oncogene (melanoma growth-stimulating activity) antibody Gro1 oncogene antibody GROa antibody GROA_HUMAN antibody Growth-regulated alpha protein antibody KC antibody KC chemokine, mouse, homolog of antibody melanoma growth stimulatory activity alpha antibody Melanoma growth stimulatory activity antibody Melanoma growth stimulatory activity, alpha antibody MGSA alpha antibody MGSA antibody MGSA-a antibody N51 antibody NAP-3 antibody NAP3 antibody Neutrophil-activating protein 3 antibody Platelet-derived growth factor-inducible protein KC antibody Scyb 1 antibody Scyb1 antibody Secretory protein N51 antibody Small inducible cytokine subfamily B, member 1 antibody
• Abbreviation: Growth-regulated alpha protein C-X-C motif chemokine 1 GRO-alpha (1-73) Melanoma growth stimulatory activity (MGSA) Neutrophil-activating protein 3 (NAP-3)
• CAS Number: 9000-83-3
• Swiss Prot: P09341 Human
• Cellular Locus: Secreted.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Recombinant protein within human CXCL1 aa 1-107.
• Isotype: IgG
• Clone: PSH07-53
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB
• Positive Control: HUVEC treated with 0.5μg/mL LPS for 24 hours cell lysate, EA.hy926 treated with 0.5μg/mL LPS for 4 hours cell lysate.
• Concentration: 1 mg/mL
• Dilution: WB:1:2,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 11 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes