Products for Research Use Only
RegisterLogin

Senkirkin

CAT: 0804-HY-122509-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-122509-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Senkirkin, a pyrrolizidine alkaloid, occured in the aerial parts of the medicinal plant Tussilago farfara, could induce chromosome damage in human lymphocytes. Senkirkin can be metabolized by CYP3A4[1].
CAS Number
2318-18-5
Product Name Alternative
Senkirkine; Renardin
UNSPSC
12352005
Hazard Statement
H300, H341
Target
Cytochrome P450
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/senkirkin.html
Purity
98.79
Solubility
10 mM in DMSO
Smiles
O=C(/C(C[C@@H](C)[C@]1(O)C)=C\C)O[C@](C2=O)([H])CCN(C)C/C=C2/COC1=O
Molecular Formula
C19H27NO6
Molecular Weight
365.42
Precautions
H300, H341
References & Citations
[1]C Kraus, G Abel, et al. [Pyrrolizidine Alkaloids With Chromosome-Damaging Effects on Human Lymphocytes in Vitro]. Planta Med. 1985 Apr; (2) :89-91.|[2]Fashe MM, et al. In silico prediction of the site of oxidation by cytochrome P450 3A4 that leads to the formation of the toxic metabolites of pyrrolizidine alkaloids. Chem Res Toxicol. 2015 Apr 20;28 (4) :702-10.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Alternative Products

CatalogName
MBS5772598Senkirkin

Popular Products