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CX546

CAT: 0804-HY-12505-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12505-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CX546 is a first-generation and selective benzamide-type positive AMPAR modulator. CX546 is a prototypical ampakine agent and has antipsychotic effects[1][2].
CAS Number
215923-54-9
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; iGluR
Type
Reference compound
Related Pathways
Autophagy; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/CX546.html
Purity
99.62
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic) |H2O : 2 mg/mL (ultrasonic)
Smiles
O=C(N1CCCCC1)C2=CC=C(OCCO3)C3=C2
Molecular Formula
C14H17NO3
Molecular Weight
247.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Lauterborn JC, et al. Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons. J Neurosci. 2000 Jan 1;20 (1) :8-21.|[2]Lipina T, et al. The ampakine CX546 restores the prepulse inhibition and latent inhibition deficits in mGluR5-deficient mice. Neuropsychopharmacology. 2007 Apr;32 (4) :745-56.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AMPA Receptor

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Alternative Products

CatalogName
T7580-01CX546
A21923-25CX546 25mg
A21923-50CX546 50mg
A21923-10CX546 10mg
A21923-200CX546 200mg
A21923-100CX546 100mg
A21923-5CX546 5mg
217296CX546 (AMPA Positive Allosteric Modulator, CX546, CX-546, CX 546)

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