2-HBA

• UNSPSC Description:

  2-HBA is a potent inducer of NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1) which can also activate caspase-3 and caspase-10.

• Target Antigen:

  Caspase

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/2-HBA.html

• Purity:

  99.09

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(/C=C/C1=CC=CC=C1O)/C=C/C2=CC=CC=C2O

• Molecular Weight:

  266.29

• References & Citations:

  [1]Dinkova-Kostova AT, et al. Bis(2-hydroxybenzylidene)acetone, a potent inducer of the phase 2 response, causes apoptosis in mouse leukemia cells through a p53-independent, caspase-mediated pathway. Cancer Lett. 2007 Jan 8;245(1-2):341-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  131359-24-5