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Batracylin

CAT: 0804-HY-119892-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-119892-01Size:1 mg
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Description
Batracylin (NSC320846) is a potent DNA Topoisomerases I and DNA Topoisomerases II inhibitor. Batracylin shows cytotoxicity and antiproliferative activity. Batracylin induces DNA breaks[1].
CAS Number
67199-66-0
Product Name Alternative
NSC 320846; BAY-H 2049
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/batracylin.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(C=CC=C2)C3=NC4=C(CN31)C=C(C=C4)N
Molecular Formula
C15H11N3O
Molecular Weight
249.27
References & Citations
[1]Rao VA, et al. Batracylin (NSC 320846), a dual inhibitor of DNA topoisomerases I and II induces histone gamma-H2AX as a biomarker of DNA damage. Cancer Res. 2007 Oct 15;67 (20) :9971-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

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