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Deferasirox (Standard)

CAT: 0804-HY-17359R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-17359R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Deferasirox (Standard) is the analytical standard of Deferasirox. This product is intended for research and analytical applications. Deferasirox (ICL 670) is an orally available iron chelator used for the management of transfusional iron overload[1][2][3].
CAS Number
201530-41-8
Product Name Alternative
ICL 670 (Standard)
UNSPSC
12352005
Hazard Statement
H302-H400
Target
Bacterial; Ferroptosis; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Apoptosis; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/deferasirox-standard.html
Smiles
O=C(O)C1=CC=C(N2N=C(C3=CC=CC=C3O)N=C2C4=CC=CC=C4O)C=C1
Molecular Formula
C21H15N3O4
Molecular Weight
373.36
Precautions
P264-P270-P273-P330-P391-P501
References & Citations
[1]Sobbe A, et al. Inconsistent hepatic antifibrotic effects with the iron chelator deferasirox. J Gastroenterol Hepatol. 2015 Mar;30 (3) :638-45.|[2]Kim JL, et al. The oral iron chelator deferasirox induces apoptosis in myeloid leukemia cells by targetingcaspase. Acta Haematol. 2011;126 (4) :241-5.|[3]Lee DH, et al. Deferasirox shows in vitro and in vivo antileukemic effects on murine leukemic cell lines regardless of iron status. Exp Hematol. 2013 Jun;41 (6) :539-46.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
Launched

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CatalogName
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