S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate
CAT:
804-HY-129942-01
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate
- CAS Number: 2127875-65-2
- UNSPSC Description: S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) and refers to the Alkyl-Chain composition. S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is the linker portions of the molecules employed for mAb attachment purposes[1].
- Target Antigen: ADC Linker
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/s-1-hydroxy-2-methylpropan-2-yl-methanesulfonothioate.html
- Purity: 95.0
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: CC(SS(C)(=O)=O)(C)CO
- Molecular Weight: 184.28
- References & Citations: [1]Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: No Development Reported