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3-Hydroxyisovaleric acid

CAT: 0804-HY-113409-01Size: 10 gDry Ice: NoHazardous: No
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CAT#:0804-HY-113409-01Size:10 g
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Description
3-Hydroxyisovaleric acid is a normal endogenous metabolite excreted in the urine. The urinary excretion of 3-hydroxyisovaleric acid is early and sensitive indicator of biotin deficiency[1][2].
CAS Number
625-08-1
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/3-Hydroxyisovaleric_acid.html
Concentration
10mM
Purity
98.92
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL
Smiles
CC(C)(O)CC(O)=O
Molecular Formula
C5H10O3
Molecular Weight
118.13
Precautions
H302, H315, H319, H335
References & Citations
[1]Mock NI, et al. Increased urinary excretion of 3-hydroxyisovaleric acid and decreased urinary excretion of biotin are sensitive early indicators of decreased biotin status in experimental biotin deficiency. 1997 Apr;65 (4) :951-8.|[2]Watanabe T, et al. Measurement of 3-hydroxyisovaleric acid in urine of biotin-deficient infants and mice by HPLC. J Nutr. 2005 Mar;135 (3) :615-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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