3-Hydroxyisovaleric acid

• Description :

  3-Hydroxyisovaleric acid is a normal endogenous metabolite excreted in the urine. The urinary excretion of 3-hydroxyisovaleric acid is early and sensitive indicator of biotin deficiency[1][2].

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Endogenous Metabolite

• Type :

  Natural Products

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/3-Hydroxyisovaleric_acid.html

• Concentration :

  10mM

• Purity :

  98.92

• Solubility :

  DMSO : 50 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

• Smiles :

  CC(C)(O)CC(O)=O

• Molecular Formula :

  C5H10O3

• Molecular Weight :

  118.13

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Mock NI, et al. Increased urinary excretion of 3-hydroxyisovaleric acid and decreased urinary excretion of biotin are sensitive early indicators of decreased biotin status in experimental biotin deficiency. 1997 Apr;65 (4) :951-8.|[2]Watanabe T, et al. Measurement of 3-hydroxyisovaleric acid in urine of biotin-deficient infants and mice by HPLC. J Nutr. 2005 Mar;135 (3) :615-8.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, stored under nitrogen)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  Human Endogenous Metabolite

• CAS Number :

  [625-08-1]