(±) -Coniine

• Description:

  (±) -Coniine (2-Propylpiperidine) is a piperidine alkaloid and nAChR agonist (EC50=0.3 mM) . (±) -Coniine is acutely toxic to mice with an LD50 value of 7.7 mg/kg[1][2].

• Product Name Alternative:

  2-Propylpiperidine

• UNSPSC:

  12352005

• Hazard Statement:

  H315-H319-H320

• Target:

  NAChR

• Type:

  Natural Products

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/racemic-coniine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCC1NCCCC1

• Molecular Formula:

  C8H17N

• Molecular Weight:

  127.23

• Precautions:

  P264-P280-P302+P352-P305+P351+P338-P362

• References & Citations:

  [1]B T Green, et al. Complete Inhibition of Fetal Movement in the Day 40 Pregnant Goat Model by the Piperidine Alkaloid Anabasine but Not Related Alkaloids. Toxicon. 2018 Mar 15;144:61-67.|[2]Lee ST, et al. Stereoselective potencies and relative toxicities of coniine enantiomers. Chem Res Toxicol. 2008 Oct;21 (10) :2061-4.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [3238-60-6]