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Pepinemab

CAT: 0804-HY-P99407-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99407-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pepinemab (VX 15/2503) is a human monoclonal antibody against SEMA4D, a signalling protein 4D (SEMA4D), also known as CD100, which is a regulator of neuronal development and plays a role in a variety of cellular processes. Pepinemab can be used in the study of various neurodegenerative diseases such as Alzheimer's disease by blocking the activity of SEMA4D[1].
CAS Number
2097151-87-4
Product Name Alternative
VX 15/2503
UNSPSC
12352203
Target
Others
Type
Inhibitory Antibodies
Related Pathways
Others
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/pepinemab.html
Purity
99.87
Solubility
10 mM in DMSO
Smiles
[Pepinemab]
Molecular Weight
(145.88 kDa)
References & Citations
[1]Elizabeth E Evans, et al. Semaphorin 4D is upregulated in neurons of diseased brains and triggers astrocyte reactivity. J Neuroinflammation. 2022 Aug 6;19 (1) :200.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2

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