Products for Research Use Only
RegisterLogin

Bindarit

CAT: 0804-HY-B0498-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B0498-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Bindarit (AF2838) is a selective inhibitor of the monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7, and MCP-2/CCL8, and no effect on other CC and CXC chemokines such as MIP-1α/CCL3, MIP-1β/CCL4, MIP-3/CCL23. Bindarit also has anti-inflammatory activity[1].
CAS Number
130641-38-2
Product Name Alternative
AF2838
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
CCR
Type
Natural Products
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease; Cancer; Endocrinology
Assay Protocol
https://www.medchemexpress.com/bindarit.html
Purity
99.53
Solubility
DMSO : ≥ 46 mg/mL
Smiles
CC(OCC1=NN(CC2=CC=CC=C2)C3=C1C=CC=C3)(C)C(O)=O
Molecular Formula
C19H20N2O3
Molecular Weight
324.37
Precautions
H302, H315, H319, H335
References & Citations
[1]Grassia, G., et al., The anti-inflammatory agent bindarit inhibits neointima formation in both rats and hyperlipidaemic mice. Cardiovasc Res, 2009. 84 (3) : p. 485-93.|[2] Zoja C, Bindarit retards renal disease and prolongs survival in murine lupus autoimmune disease. Kidney Int. 1998 Mar;53 (3) :726-34.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Phase 3

Alternative Products

CatalogName
MBS3601224-01Bindarit

Popular Products