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(Rac) -AB-423

CAT: 0804-HY-112142ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-112142ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(Rac) -AB-423 (DVR-23) is an anti-HBV candidate compound with promising anti-HBV activity. (Rac) -AB-423 showed no induction of CYP1A2, CYP3A4, or CYP2B6 enzyme activity at high concentrations. (Rac) -AB-423 exhibited desirable pharmacokinetic properties, enabling good systemic exposure and high oral bioavailability. (Rac) -AB-423 achieved more than 2 log viral load reduction in the hydrodynamic injection (HDI) HBV mouse model[1].
CAS Number
422547-55-5
Product Name Alternative
DVR-23
UNSPSC
12352005
Target
HBV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/rac-ab-423.html
Smiles
O=C(NC1=CC=C(F)C(F)=C1)C2=CC(S(=O)(NC(C)CC)=O)=CC=C2F
Molecular Formula
C17H17F3N2O3S
Molecular Weight
386.39
References & Citations
[1]3- ((R) -4- (((R) -6- (2-Bromo-4-fluorophenyl) -5- (ethoxycarbonyl) -2- (thiazol-2-yl) -3,6-dihydropyrimidin-4-yl) methyl) morpholin-2-yl) propanoic Acid (HEC72702), a Novel Hepatitis B Virus Capsid Inhibitor Based on Clinical Candidate GLS4
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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