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DCOIT

CAT: 0804-HY-W041308-01Size: 5 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W041308-01Size:5 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DCOIT is a representative isothiazolinone that stimulates the gonadotropin-releasing hormone receptor (GnRHR) -mediated synthesis of follicle-stimulating hormone and luteinizing hormone in the brain. DCOIT interferes with G protein-coupled receptors, MAPK and Ca2+ signaling cascades[1].
CAS Number
64359-81-5
Product Name Alternative
Kathon 930
UNSPSC
12352005
Hazard Statement
H302, H314, H317, H330, H410
Target
GnRH Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/dcoit.html
Concentration
10mM
Purity
99.87
Solubility
DMSO : 133.33 mg/mL (ultrasonic)
Smiles
O=C1N(CCCCCCCC)SC(Cl)=C1Cl
Molecular Formula
C11H17Cl2NOS
Molecular Weight
282.23
Precautions
H302, H314, H317, H330, H410
References & Citations
[1]Tang L, et al. Isothiazolinone Disrupts Reproductive Endocrinology by Targeting the G-Protein-Coupled Receptor Signaling. Environ Sci Technol. 2024 Jan 3.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
T84706-01DCOIT

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