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Phospho-EIF2AK2 (T446) Antibody

CAT: 0864-A40044-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0864-A40044-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Aliases
Double stranded RNA activated protein kinase, E2AK2_HUMAN, eIF-2A protein kinase 2, EIF2AK1, EIF2AK2, Eukaryotic translation initiation factor 2 alpha kinase 2, Eukaryotic translation initiation factor 2-alpha kinase 2, HGNC:9437, Interferon induced double stranded RNA activated protein kinase, Interferon inducible elF2 alpha kinase , Interferon inducible RNA dependent protein kinase, Interferon-induced, double-stranded RNA-activated protein kinase, Interferon-inducible RNA-dependent protein kinase, MGC126524, P1/eIF-2A protein kinase, P1/eIF2A protein kinase , p68 kinase, PKR, PPP1R83, PRKR, Protein kinase interferon inducible double stranded RNA dependent, Protein kinase RNA activated, Protein kinase RNA-activated, Protein phosphatase 1 regulatory subunit 83, Serine/threonine protein kinase TIK , Tyrosine protein kinase EIF2AK2
UniProt
P19525
Host
Rabbit
Antigen Species
Human
Reactivity
Human
Target Antigen
Synthesized peptide derived from Human PKR around the phosphorylation site of T446.
Target
EIF2AK2
Clonality
Polyclonal
Conjugation
Non-conjugated
Applications
WB, ELISA, WB:1:500-1:2000, ELISA:1:10000
Field of Research
Signal Transduction
Purification Method
Antigen affinity purified
Form
Liquid
Buffer
PBS, 50% glycerol, 0.5% BSA, 0.02% sodium azide, pH 7.4.
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Fragment
IgG

UniProtKB · P19525

Interferon-induced, double-stranded RNA-activated protein kinase

E2AK2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P19525
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EIF2AK2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
A8K3P0, D6W584, E9PC80, Q52M43, Q7Z6F6, Q9UIR4
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

Antiviral defenseHost-virus interactionImmunityInnate immunityTranscriptionTranscription regulation

Ligand

ATP-bindingMagnesiumNucleotide-binding

Cellular component

CytoplasmNucleus

Disease

Disease variantDystonia

Molecular function

KinaseRNA-bindingSerine/threonine-protein kinaseTransferaseTyrosine-protein kinase

Domain

Repeat