HDAC8-IN-8
CAT:
804-HY-124782-03
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HDAC8-IN-8
- CAS Number: 1884231-52-0
- UNSPSC Description: HDAC8-IN-8 (15a) is an HDAC8 inhibitor, with IC50 values of 23.9 μM and 268.2 μM for hHDAC8 and smHDAC8 respectively. And for hHDAC1 and hHDAC6, the IC50 values are 12.1 μM and 2.9 μM respectively. HDAC8-IN-8 can be used in schistosomiasis-related research[1].
- Target Antigen: HDAC
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Epigenetics
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/hdac8-in-8.html
- Purity: 99.01
- Solubility: 10 mM in DMSO
- Smiles: O=C(C1=CC=C(C(OCC2=CC=CC=C2)=C1)OC)NO
- Molecular Weight: 273.28
- References & Citations: [1]Heimburg T, et al. Structure-Based Design and Synthesis of Novel Inhibitors Targeting HDAC8 from Schistosoma mansoni for the Treatment of Schistosomiasis. J Med Chem. 2016 Mar 24;59(6):2423-35.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported