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Pasiniazid

CAT: 0804-HY-B1048-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1048-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pasiniazid is a chemical complex formed by Isoniazid and Para-aminosalicylic acid in a 1:1 molar ratio. Pasiniazid is an antibacterial agent. Pasiniazid is rapidly decomposed into isoniazid and para-aminosalicylic acid in the gastrointestinal tract. Isoniazid exerts a bactericidal effect, while para-aminosalicylic acid delays the acetylation process of isoniazid. Pasiniazid has antibacterial activity against Mycobacterium tuberculosis. Pasiniazid can be used in tuberculosis research[1].
CAS Number
2066-89-9
Product Name Alternative
Paraniazide; Pasiniazide; Isonicotinic acid hydrazide p-aminosalicylate
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Pasiniazid.html
Purity
98.2
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=NC=C1)NN.O=C(O)C2=CC=C(N)C=C2O
Molecular Formula
C13H14N4O4
Molecular Weight
290.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Li G, et al. Cross-resistance of isoniazid, para-aminosalicylic acid and pasiniazid against isoniazid-resistant Mycobacterium tuberculosis isolates in China. J Glob Antimicrob Resist. 2020 Mar;20:275-281.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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